let's start: what is down syndrome?
Down syndrome is a condition in which a person has an extra chromosome. Chromosomes are small “packages” of genes in the body. They determine how a baby’s body forms and functions as it grows during pregnancy and after birth. Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is ‘trisomy.’ Down syndrome is also referred to as Trisomy 21. This extra copy changes how the baby’s body and brain develop, which can cause both mental and physical challenges for the baby.

Some common physical features of Down syndrome include:

A flattened face, especially the bridge of the nose
Almond-shaped eyes that slant up
A short neck
Small ears
A tongue that tends to stick out of the mouth
Tiny white spots on the iris (colored part) of the eye
Small hands and feet
A single line across the palm of the hand (palmar crease)
Small pinky fingers that sometimes curve toward the thumb
Poor muscle tone or loose joints
Shorter in height as children and adults

for some reference, here's a cat with down syndrome


Ideas on how it could affect the lion-
-in cub training, the could be a bit aloof, and have trouble with focusing on training
"(Cub) tried to focus but fell, giggling as they flopped on their belly"
-if brought on hunts, they could be described to "chase butterflies instead" and bring home butterflies instead of prey

only some ideas <3 would be a really cool mutation!

If you don't support, please comment why, don't just do it with no explanation