You can get mutated cubs from lionesses with any fertility - it isn't limited to VLFs. It's just that the chance of muties very slightly increases the lower their fertility is, so if you're hardcore breeding for muties then VLFs may be advantageous. The downsides are that if your lioness has extremely low fertility it can take a ton of breeding attempts - and therefore a ton of energy - to get her successfully pregnant. For instance 1% lionesses can often take hundreds of tries.

Goddess fertility has basically the opposite pros/cons. On the upside they have 100% fertility, so they are the easiest to breed since they're guaranteed to get pregnant on the very first attempt. On the downside their higher fertility means a slightly lower chance of 'natural' mutie cubs (i.e. random ones - not those based on using mutation items like GMOs etc). For what it's worth though a lot of my random muties have actually come from mothers with higher fertilities, so I'm not sure there's a huge difference to be honest.

Basically it just comes down to what people's individual priorities are :)

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